Synthesis of structurally diverse pyrazolo[1,2-<i>a</i>]pyrazolones based on the selective C–H bond alkenylation–annulation of 1-arylpyrazolidinones with allenyl acetates
Yongdi Xin, Qianting Zhou, Bin Li, Biao Cheng, Xinying Zhang, Xuesen Fan
Abstract
Presented herein is a concise synthesis of diverse pyrazolo[1,2- a ]pyrazolones based on condition-controlled divergent reactions of 1-arylpyrazolidinones with allenyl acetates.
Topics & Concepts
PyrazolonesAnnulationChemistryCombinatorial chemistryMedicinal chemistryStereochemistryOrganic chemistryCatalysisCatalytic C–H Functionalization MethodsSynthesis of heterocyclic compoundsSynthesis and biological activity