Copper-catalysed synthesis of trifluoromethyl allenes <i>via</i> fluoro-carboalkynylation of alkenes
Mengning Wang, Qiuzhu Wang, Mengtao Ma, Binlin Zhao
Abstract
A copper-catalysed three-component reaction utilizing readily available feedstocks was investigated, providing an operationally simple and practical route to trifluoromethyl allenes under mild and environmentally friendly conditions.
Topics & Concepts
ChemistryTrifluoromethylCopperEnvironmentally friendlyOrganic chemistryCombinatorial chemistryAlkylBiologyEcologyFluorine in Organic ChemistryCatalytic C–H Functionalization MethodsCyclopropane Reaction Mechanisms