A matrix metalloproteinase-responsive hydrogel delivers dendritic cell-targeting nanoparticles for sustained antitumor immunity
Yijun Wu, Jiaxuan Yang, Yunan Yuan, Fujiang Li, Ruonan Huang, Cheng Qian, Yan Rong, Xuesi Chen, Chaoliang He
Topics & Concepts
ChemistryImmune systemSelf-healing hydrogelsTumor microenvironmentCancer researchMelanomaImmunogenic cell deathDrug deliveryCancer immunotherapyImmunotherapyDendritic cellOxaliplatinMatrix metalloproteinaseLymph nodeDrugCancer cellImmunitySystemic administrationCancerCancer vaccineNanoparticleImmunologyLymphNanocarriersCytotoxic T cellDrug carrierAcquired immune systemMatrix (chemical analysis)Nanoplatforms for cancer theranosticsImmunotherapy and Immune ResponsesImmune cells in cancer