MOF(Fe)-derived composites as a unique nanoplatform for chemo-photodynamic tumor therapy
Zhimin Mo, Xinyuan Pan, Xiaoli Pan, Lin Ye, Han Hu, Qi Xu, Xiaoxi Hu, Zushun Xu, Jie Xiong, Guangfu Liao, Shengli Yang
Abstract
experiments showed that the MNMCF-guided CDT/PDT combination therapy could effectively ablate tumors without the drawbacks of poor tolerability and potential long-term side effects. Therefore, the prepared MNMCF NPs can be used as promising candidates for synergistic CDT/PDT tumor therapy.
Topics & Concepts
Photodynamic therapyBiocompatibilityPhotosensitizerMaterials scienceIn vivoTumor microenvironmentTolerabilityNanotechnologyNanoparticleSmall moleculeCombination therapyAdsorptionMetal-organic frameworkCancer researchChemistryPharmacologyPhotochemistryTumor cellsMedicineAdverse effectOrganic chemistryBiochemistryBiotechnologyBiologyMetallurgyNanoplatforms for cancer theranosticsAdvanced Nanomaterials in CatalysisNanoparticle-Based Drug Delivery