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Autism genes converge on asynchronous development of shared neuron classes

Bruna Paulsen, Silvia Velasco, Amanda J. Kedaigle, Martina Pigoni, Giorgia Quadrato, Anthony J. Deo, Xian Adiconis, Ana Uzquiano, Rafaela Sartore, Sung Min Yang, Sean Simmons, Panagiotis Symvoulidis, Kwanho Kim, Kalliopi Tsafou, Archana Podury, Catherine Abbate, Ashley Tucewicz, Samantha N. Smith, Alexandre Albanese, Lindy E. Barrett, Neville E. Sanjana, Xi Shi, Kwanghun Chung, Kasper Lage, Edward S. Boyden, Aviv Regev, Joshua Z. Levin, Paola Arlotta

2022Nature461 citationsDOIOpen Access PDF

Topics & Concepts

BiologyHaploinsufficiencyPhenotypeContext (archaeology)AutismNeuroscienceGeneGeneticsNeurodevelopmental disorderCell typeCellPsychologyPaleontologyDevelopmental psychologySingle-cell and spatial transcriptomicsCRISPR and Genetic EngineeringGenomics and Chromatin Dynamics
Autism genes converge on asynchronous development of shared neuron classes | Litcius