Tank Binding Kinase 1 modulates spindle assembly checkpoint components to regulate mitosis in breast and lung cancer cells
Meenu Maan, Neha Jaiswal, Jaya Padmanabhan, Christelle Colin, Yainyrette Rivera-Rivera, Harold I. Saavedra, Srikumar Chellappan
Topics & Concepts
Spindle checkpointCDC20Cell biologyAnaphase-promoting complexMitosisPLK1BiologyAnaphaseKinetochoreSpindle apparatusCentrosomeCell cycle checkpointCancer researchUbiquitin ligaseCDH1ChemistryCell cycleCell divisionUbiquitinCancerCellGeneticsCadherinChromosomeGeneMicrotubule and mitosis dynamicsUbiquitin and proteasome pathwaysGenomics and Chromatin Dynamics