Systematic comparison of racemic and enantiopure multicomponent crystals of phenylsuccinic acid—the role of chirality
Jean-Eudes Odounga Odounga, Nikoletta B. Báthori
Abstract
Comparison of binary cocrystals of chiral and racemic carboxylic acids showed that the introduction of chiral building blocks may lead to the formation of subclasses of multicomponent crystals with unique <italic>Z</italic>′′/<italic>Z</italic><sup>r</sup> values combined with complex protonation stages of the molecules.
Topics & Concepts
Enantiopure drugChirality (physics)ProtonationMoleculeChemistryBinary numberStereochemistryCrystallographyComputational chemistryOrganic chemistryChiral symmetryEnantioselective synthesisMathematicsPhysicsCatalysisArithmeticNambu–Jona-Lasinio modelIonQuantum mechanicsQuarkCrystallography and molecular interactionsCrystallization and Solubility StudiesCrystal structures of chemical compounds