Litcius/Paper detail

Highly Efficient Adsorption of Bilirubin by Ti<sub>3</sub>C<sub>2</sub>T<sub>x</sub> MXene

Xiaoyu Sun, Jian Yang, Dawei Su, Chengyin Wang, Guoxiu Wang

2021Chemistry - An Asian Journal47 citationsDOI

Abstract

Abstract We discovered that the 2D Ti 3 C 2 T x MXene sheet displays an ultra‐high removal capability for bilirubin (BR). In particular, MXene shows 47.6 times higher removal efficiency over traditional activated carbon absorbents. The effect of MXene on the removal rate of BR in BR solution containing different concentrations of bovine serum albumin (BSA) was studied. The adsorption capacity of BSA for BR at high concentration of 5 g L −1 was about 85% of the best adsorption capacity. The MXene before and after adsorption was characterized by SEM, FT‐IR and XPS. Furthermore, MXene beads were prepared, and the hemoperfusion simulation experiment was carried out. The results show that the adsorption capacity of MXene for bilirubin can reach 1192.9 mg g −1 . This study suggests that MXene may be promising in the treatment of hyperbilirubinemia.

Topics & Concepts

AdsorptionHemoperfusionX-ray photoelectron spectroscopyBilirubinChemistryActivated carbonBovine serum albuminNuclear chemistryMaterials scienceInorganic chemistryChemical engineeringChromatographyOrganic chemistrySurgeryHemodialysisGastroenterologyEngineeringMedicineMXene and MAX Phase MaterialsGraphene and Nanomaterials ApplicationsAdenosine and Purinergic Signaling