High-throughput simultaneous quantification of five azole anti-fungal agents and one active metabolite in human plasma using ultra-high-performance liquid chromatography coupled to tandem mass spectrometry
Ryota Tanaka, Ken Shiraiwa, Kuniko Takano, Masao Ogata, Shuhei Honda, Natsumi Yoshida, Kazuki Okuhiro, Masaki Yoshida, Kumiko Narahara, Makoto Kai, Ryosuke Tatsuta, Hiroki Itoh
Topics & Concepts
ChemistryChromatographyTherapeutic drug monitoringItraconazoleActive metaboliteFluconazoleMetabolitePharmacokineticsPharmacologyAntifungalMedicineBiochemistryDermatologyAntifungal resistance and susceptibilityNail Diseases and TreatmentsFungal Infections and Studies