Design, microwave assisted synthesis, and molecular modeling study of some new 1,3,4-thiadiazole derivatives as potent anticancer agents and potential VEGFR-2 inhibitors
Saad R. Atta‐Allah, Asmaa M. AboulMagd, Paula S. Farag
Topics & Concepts
ChemistryNucleophilePyrimidineThiopheneElectrophileNucleophilic substitutionDocking (animal)StereochemistryIC50Combinatorial chemistryMedicinal chemistryOrganic chemistryIn vitroBiochemistryMedicineNursingCatalysisSynthesis and biological activitySynthesis and Characterization of Heterocyclic CompoundsMulticomponent Synthesis of Heterocycles