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Neuregulin 4 alleviates hepatic steatosis via activating AMPK/mTOR-mediated autophagy in aged mice fed a high fat diet

Biao Zhu, Wen Mei, Ting Jiao, Shuo Yang, Xiaoli Xu, Hanying Yu, Yan Ding, Shuqin Guo, Biying Meng, Lisheng Zhao, Mingjuan He, Keming Dong, Hongyan Guo, Ximin Guo, Haisong Zhang, Ruijie Dang, Guangda Xiang, Ning Wen

2020European Journal of Pharmacology29 citationsDOI

Topics & Concepts

AutophagyAMPKSteatosisPI3K/AKT/mTOR pathwayEndocrinologyInternal medicineMechanistic target of rapamycinLipid dropletFatty liverProtein kinase ASignal transductionChemistryBiologyMedicineCell biologyKinaseApoptosisBiochemistryDiseaseAutophagy in Disease and TherapyPancreatic function and diabetesMetabolism, Diabetes, and Cancer
Neuregulin 4 alleviates hepatic steatosis via activating AMPK/mTOR-mediated autophagy in aged mice fed a high fat diet | Litcius