Synthesis and evaluation of naphthalene derivatives as potent STAT3 inhibitors and agents against triple-negative breast cancer growth and metastasis
Zhengyan Yang, Hongyun Xu, Yupo Yang, Chaoqun Duan, Pai Zhang, Yang Wang, Kai Fu, Yonghong Shen, Marvin Xuejun Xu
Topics & Concepts
Cancer researchSTAT3Triple-negative breast cancerBreast cancerMetastasisCyclin D1STAT proteinEstrogen receptorCell growthBiologySignal transductionCancerChemistryCell cycleMedicineInternal medicineCell biologyBiochemistryCytokine Signaling Pathways and InteractionsSynthesis and biological activityNF-κB Signaling Pathways