Litcius/Paper detail

Discovery of novel BTK PROTACs for B-Cell lymphomas

Yunpeng Zhao, Yongzhi Shu, Jun Lin, Zhendong Chen, Qiong Xie, Yanning Bao, Lixue Lu, Nannan Sun, Yonghui Wang

2021European Journal of Medicinal Chemistry40 citationsDOIOpen Access PDF

Topics & Concepts

Bruton's tyrosine kinaseChemistryTyrosine kinaseIbrutinibMutantCovalent bondCancer researchBiochemistryBiologySignal transductionChronic lymphocytic leukemiaImmunologyGeneLeukemiaOrganic chemistryProtein Degradation and InhibitorsChronic Lymphocytic Leukemia ResearchMultiple Myeloma Research and Treatments