Interleukin-1β converting enzyme (ICE): A comprehensive review on discovery and development of caspase-1 inhibitors
Palmi Modi, Bhumi Shah, Shivani Patel
Topics & Concepts
AnakinraCaspase 1PeptidomimeticCanakinumabPharmacologyChemistryCaspaseSmall moleculeMediatorDrug discoveryInflammationMedicineDiseaseImmunologyApoptosisPeptideBiochemistryInflammasomeInternal medicineProgrammed cell deathInflammasome and immune disordersCell death mechanisms and regulationinterferon and immune responses