β-Elemonic acid inhibits the growth of human Osteosarcoma through endoplasmic reticulum (ER) stress-mediated PERK/eIF2α/ATF4/CHOP activation and Wnt/β-catenin signal suppression
Ang Zhao, Zhanjie Zhang, Yanfen Zhou, Xin Li, Xiaotian Li, Bo Ma, Qi Zhang
Topics & Concepts
Unfolded protein responseViability assayApoptosisCell cycleCancer researchEndoplasmic reticulumWnt signaling pathwayCell growthCell cycle checkpointCHOPBiologyChemistryCell biologySignal transductionBiochemistryPharmacological Effects of Medicinal PlantsNatural product bioactivities and synthesisImmune Response and Inflammation