Leptomeningeal metastasis from solid tumours: EANO–ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up
Émilie Le Rhun, Michael Weller, Martin J. van den Bent, Dieta Brandsma, Julia Furtner, Roberta Rudà, Dirk Schadendorf, Joan Seoane, J.-C. Tonn, Pieter Wesseling, Wolfgang Wick, Giuseppe Minniti, Solange Peters, Giuseppe Curigliano, Matthias Preusser
Abstract
•This Clinical Practice Guideline provides recommendations for managing leptomeningeal metastases from solid tumours.•The guideline covers clinical, imaging and cytological diagnosis, staging and risk assessment, treatment and follow-up.•A treatment and management algorithm is provided.•The author panel encompasses a multidisciplinary group of experts from different institutions and countries in Europe.•Recommendations are based on available scientific data and the authors’ collective expert opinion.