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Ultrahigh-Speed Spectral-Domain Optical Coherence Tomography up to 1-MHz A-Scan Rate Using Space–Time-Division Multiplexing

Daewoon Seong, Deokmin Jeon, Ruchire Eranga Wijesinghe, Kibeom Park, Hyeree Kim, Euimin Lee, Mansik Jeon, Jeehyun Kim

2021IEEE Transactions on Instrumentation and Measurement30 citationsDOIOpen Access PDF

Abstract

The primary optimization of the imaging speed of optical coherence tomography (OCT) has been keenly studied. In order to overcome the major speed limitation of spectral-domain OCT (SD-OCT), we developed an ultrahigh-speed SD-OCT system, with an A-scan rate of up to 1 MHz, using the method of space–time-division multiplexing (STDM). Multicameras comprising a single spectrometer were implemented in the developed ultrahigh-speed STDM method to eliminate the dead time of operation, whereas STDM was simultaneously employed to enable wide-range scanning measurements at a high speed. By successfully integrating the developed STDM method with GPU parallel processing, 8 vol/s for an image range of <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$250\times 250\times2048$ </tex-math></inline-formula> pixels ( <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$9\times 4.5\times 5$ </tex-math></inline-formula> mm) was achieved, with an adjustable volume rate according to the required scanning speed and range. The examined STDM-OCT results of the customized optical thin film confirmed its feasibility for various fields that require rapid and wide-field scanning.

Topics & Concepts

Optical coherence tomographyMultiplexingComputer sciencePixelSpeedupCoherence (philosophical gambling strategy)Range (aeronautics)OpticsAlgorithmArtificial intelligenceMathematicsPhysicsTelecommunicationsParallel computingEngineeringStatisticsAerospace engineeringOptical Coherence Tomography ApplicationsPhotoacoustic and Ultrasonic ImagingRetinal and Macular Surgery