De novo design of self-assembly hydrogels based on Fmoc-diphenylalanine providing drug release
Xiang Li, Huijun Zhang, Lingyan Liu, Chunyan Cao, Peng Wei, Xin Yi, Yifeng Zhou, Qingyang Lv, Dongfang Zhou, Tao Yi
Abstract
π-stacking of Fmoc-FF, which are supported by circular dichroism and fluorescence emission spectroscopy. Rheology results confirm that the hydrogel of Fmoc-FFRRVR is elastic, reversible and injectable. The newly discovered hydrogel not only retains some excellent performances of Fmoc-FF, but also can be used as a drug carrier for biomedical applications.
Topics & Concepts
Self-healing hydrogelsMaterials scienceDrugNanotechnologySelf-assemblyCancer therapySelf-healingCombinatorial chemistryCancerPharmacologyPolymer chemistryChemistryMedicinePathologyInternal medicineAlternative medicineSupramolecular Self-Assembly in MaterialsHydrogels: synthesis, properties, applicationsRNA Interference and Gene Delivery