Litcius/Paper detail

Prevalence and causes of clinically detectable uveitic serous retinal detachment

Robert M. Kinast, Sharon D. Solomon, Leo Dp Cubillan, Anna Hovakimyan, Nisha R. Acharya, Emmett T. Cunningham

2021European Journal of Ophthalmology11 citationsDOI

Abstract

PURPOSE: To describe the prevalence and causes of clinically detectable uveitic serous retinal detachment (SRD). METHODS: Retrospective chart review of a large clinic-based series. RESULTS: Serous retinal detachment was present in 78 of the 2761 (2.8%) patients. Vogt-Koyanagi-Harada (VKH) disease was the most commonly identified cause (38/78, 48.7%). Less common associated etiologies included toxoplasmic retinochoroiditis (8/78, 10.3%), sarcoidosis (5/78, 6.4%), intraocular lymphoma (4/78, 5.1%), presumed tuberculosis (3/78, 3.8%), and posterior scleritis (2/78, 2.6%). Fifteen patients (19.2%) with uveitic SRD at presentation had no identifiable etiology and were labeled idiopathic or indeterminant. Thirty of the 38 patients with VKH disease (78.9%) had positive neurological and/or integumentary findings, and therefore constituted either complete or incomplete subtypes of the disease. The remaining eight (21.1%) had presumed/ocular VKH disease limited to the eye. CONCLUSION: While VKH disease by far is the most common cause of clinically detectable uveitic SRD, a number of other non-infectious and infectious inflammatory disorders were also associated with this distinctive clinical finding.

Topics & Concepts

MedicineVogt–Koyanagi–Harada diseaseEtiologyUveitisSarcoidosisRetinal detachmentOphthalmologySerous fluidScleritisDermatologyEye diseasePathologyRetinalOcular Diseases and Behçet’s SyndromeCNS Lymphoma Diagnosis and TreatmentSarcoidosis and Beryllium Toxicity Research