Optimization of dextran sulfate/poly-l-lysine based nanogels polyelectrolyte complex for intranasal ovalbumin delivery
Angela Bonaccorso, Claudia Carbone, Barbara Tomasello, Paola Italiani, Teresa Musumeci, Giovanni Puglisi, Rosario Pignatello
Topics & Concepts
Nasal administrationImmunogenicityOvalbuminResponse surface methodologySurface chargeChitosanChemistryImmune systemSyneresisPhosphate buffered salinePolyelectrolyteAntigenMaterials scienceChemical engineeringChromatographyPolymerImmunologyBiochemistryBiologyPhysical chemistryOrganic chemistryEngineeringAdvanced Drug Delivery SystemsImmunotherapy and Immune ResponsesRNA Interference and Gene Delivery