Decreasing Arl4c expression by inhibition of AKT signal in human lung adenocarcinoma cells
Yipeng Sun, Zhuhua Zhang, Fenfen Xiang, Mengzhe Zhang, Qingge Chen, Lingling Tang, Linyun Zhu, Jinjin Liu, Ziyu Meng, Junsheng Hu, Xuming Luo, Zhenhua Ni, Xiongbiao Wang
Topics & Concepts
A549 cellProtein kinase BCancer researchGene knockdownGene silencingLY294002Lung cancerSmall interfering RNAMG132PI3K/AKT/mTOR pathwayAdenocarcinomaWestern blotChemistryCancer cellBiologyCancerMolecular biologySignal transductionProteasome inhibitorCell biologyCell cultureMedicineProteasomeTransfectionPathologyApoptosisBiochemistryGeneGeneticsLung Cancer Treatments and MutationsLung Cancer Research StudiesProtein Degradation and Inhibitors