Biotinylated photoactive Pt(<scp>iv</scp>) anticancer complexes
Huayun Shi, Cinzia Imberti, Huaiyi Huang, Ian Hands-Portman, Peter J. Sadler
Abstract
(biotin)(OH)] (2a) were enhanced significantly when bound to avidin; irradiation induced dramatic cellular morphological changes in human ovarian cancer cells treated with 2a.
Topics & Concepts
BiotinylationChemistryBiophysicsCombinatorial chemistryBiochemistryBiologyMetal complexes synthesis and propertiesPhotochromic and Fluorescence ChemistryMolecular Junctions and Nanostructures