Advancements in CRISPR/Cas systems for disease treatment
Yangsong Xu, Hao Le, Qinjie Wu, Ning Wang, Changyang Gong
Abstract
applications of CRISPR systems. The efficiency of CRISPR systems in disease treatment is directly influenced by the performance of the delivery system. Additionally, concerns such as off-target effects present crucial hurdles in the clinical implementation of CRISPR systems. This review provides a comprehensive overview of the development of CRISPR systems, vector technologies, and their applications in disease treatment, while also addressing the challenges encountered in clinical settings. Furthermore, future research directions are outlined to pave the way for advancements in CRISPR-based therapies.
Topics & Concepts
CRISPRComputer scienceComputational biologyMedicineBiologyGeneticsGeneCRISPR and Genetic EngineeringInnovation and Socioeconomic DevelopmentViral Infections and Immunology Research