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A model for COVID-19 and bacterial pneumonia coinfection with community- and hospital-acquired infections

Ángel Pérez, David A. Oluyori

2022Mathematical Modelling and Numerical Simulation with Applications25 citationsDOIOpen Access PDF

Abstract

We propose a new epidemic model to study the coinfection dynamics of COVID-19 and bacterial pneumonia, which is the first model in the literature used to describe mathematically the interaction of these two diseases while considering two infection ways for pneumonia: community-acquired and hospital-acquired transmission. We show that the existence and local stability of equilibria depend on three different parameters, which are interpreted as the basic reproduction numbers of COVID-19, bacterial pneumonia, and bacterial population in the hospital. Numerical simulations are performed to complement our theoretical analysis, and we show that both diseases can persist if the basic reproduction number of COVID-19 is greater than one.

Topics & Concepts

CoinfectionPneumoniaBasic reproduction numberCoronavirus disease 2019 (COVID-19)Bacterial pneumoniaTransmission (telecommunications)MedicineIntensive care medicinePopulationComplement (music)BiologyVirologyComputer scienceInternal medicineInfectious disease (medical specialty)DiseaseHuman immunodeficiency virus (HIV)Environmental healthPhenotypeGeneBiochemistryTelecommunicationsComplementationCOVID-19 epidemiological studiesMathematical and Theoretical Epidemiology and Ecology Models
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