Human umbilical cord mesenchymal stem cells improve the ovarian function through oxidative stress-mediated PERK/eIF-2α/ATF4/CHOP signaling in premature ovarian insufficiency mice
Peiling Wu, Shihuan Tang, Hanyue Wang, Hongmei Zhang, Peng Lü, Yao Liu, Yuan Yang, Chunbing Zheng, Xianping Zhang
Topics & Concepts
CHOPTUNEL assayUnfolded protein responsePremature ovarian insufficiencyMesenchymal stem cellApoptosisPremature ovarian failureAndrologyOvarian follicleBiologyEndocrinologyInternal medicineOvaryMedicineCell biologyBiochemistryEndoplasmic Reticulum Stress and DiseaseReproductive Biology and FertilityOvarian function and disorders