Overcoming microenvironmental resistance to PD-1 blockade in genetically engineered lung cancer models
Amaia Martínez-Usatorre, Ece Kadioglu, Gaël Boivin, Chiara Cianciaruso, Alan Guichard, Bruno Torchia, Nadine Zangger, Sina Nassiri, Ioanna Keklikoglou, Martina Schmittnaegel, Carola H. Ries, Etienne Meylan, Michele De Palma
Abstract
T cells, and improved the efficacy of antiangiogenic immunotherapy, achieving regression of most tumors.
Topics & Concepts
Genetically engineeredBlockadeLung cancerCancer researchGenetically modified organismCancerAcquired resistanceMedicineBiologyGeneticsPathologyReceptorInternal medicineGeneCancer Immunotherapy and BiomarkersImmune cells in cancerPeptidase Inhibition and Analysis