Molecular basis of junctional current rectification at an electrical synapse
Yuan Shui, Ping Liu, Haiying Zhan, Bojun Chen, Zhao‐Wen Wang
Abstract
mutant. Neutralizing charged residues in UNC-7b amino terminus abolished the rectification property of UNC-7b/UNC-9 GJs. Our results suggest that the rectification property results from electrostatic interactions between charged residues in UNC-7b amino terminus.
Topics & Concepts
Electrical SynapsesGap junctionGene isoformCaenorhabditis elegansRectificationCell biologyAntidromicMutantBiologyChemistryBiophysicsPhysicsNeuroscienceGeneticsGeneStimulationQuantum mechanicsPower (physics)IntracellularGenetics, Aging, and Longevity in Model OrganismsNeurobiology and Insect Physiology ResearchConnexins and lens biology