A Zinc Coordination Polymer Sensor for Selective and Sensitive Detection of Doxycycline Based on Fluorescence Enhancement
Ahui Sun, Yonghang Yang, Yanfeng Liu, Lu Ding, Pan Duan, Weiting Yang, Qinhe Pan
Abstract
In this work, a novel coordination polymer HNU-55 has been synthesized by the reaction of Zn(II) ion with the organic ligand 3-pyridinesulfonic acid (PSA) under solvothermal condition, which can be used as a fluorescent sensor for the detection of doxycycline (DOX). The fluorescent performance is effective in a wide linear range from 0 to 30 μM of DOX with a low detection limit of 3.7 nM. Likewise, the fluorescent sensor presents good selectivity, anti-interference, and circularity. Additionally, the HNU-55 sensor can be successfully used to assay the content of DOX in pig feed. Furthermore, the mechanism of fluorescence enhancement has been discussed in detail, which provides a clear understanding for the antibiotic detection based on the fluorescence enhancement.