Deep neural networks predict class I major histocompatibility complex epitope presentation and transfer learn neoepitope immunogenicity
Benjamin Alexander Albert, Yunxiao Yang, Xiaoshan M. Shao, Dipika Singh, Kellie N. Smith, Valsamo Anagnostou, Rachel Karchin
Topics & Concepts
ImmunogenicityEpitopeMajor histocompatibility complexComputational biologyMHC class IComputer scienceHuman leukocyte antigenImmunologyAntigenBiologyvaccines and immunoinformatics approachesImmunotherapy and Immune ResponsesRNA and protein synthesis mechanisms