<i>Lactobacillus johnsonii</i> enhances the gut barrier integrity <i>via</i> the interaction between GAPDH and the mouse tight junction protein JAM-2
Yuying Bai, Mengying Lyu, Moe Fukunaga, Shin Watanabe, Shun Iwatani, Kazuhiko Miyanaga, Naoyuki Yamamoto
Abstract
GAPDH-JAM-2 binding. Here, we propose a promising approach to identify novel gut receptor molecules based on commensal bacterial interactions and understand host-bacterial communication in a mouse model.
Topics & Concepts
Tight junctionBiologyReceptorGlyceraldehyde 3-phosphate dehydrogenaseCell biologyDownregulation and upregulationGut floraMolecular biologyBiochemistryMicrobiologyDehydrogenaseEnzymeGeneGut microbiota and healthBarrier Structure and Function StudiesClostridium difficile and Clostridium perfringens research