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Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel

Kirill D. Nadezhdin, Arthur Neuberger, Yu. A. Trofimov, Nikolay A. Krylov, Viktor Sinica, Nikita Kupko, Viktorie Vlachová, Eleonora Zakharian, Roman G. Efremov, Alexander I. Sobolevsky

2021Nature Structural & Molecular Biology175 citationsDOIOpen Access PDF

Topics & Concepts

Transient receptor potential channelBiophysicsChemistryConformational changeGatingLinkerMolecular dynamicsProtein structureReceptorBiochemistryBiologyComputational chemistryComputer scienceOperating systemIon Channels and ReceptorsNeurobiology and Insect Physiology ResearchBiochemical Analysis and Sensing Techniques
Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel | Litcius