Nanotechnology-enabled therapies improve blood-brain barrier challenges in brain tumor
Yan Wenqi, Wei Lingxi, Arshad Mehmood, Wahid Shah
Abstract
The treatment of brain tumors has been predominantly hindered by the limited ability of drugs to penetrate the blood-brain barrier. However, recent advancements in nanotechnology have presented a therapeutic potential by facilitating the delivery of drugs and macromolecules across the blood-brain barrier. These nanotechnology-enabled treatments target tumor cells, exploit tumor biology, enhance the pharmacokinetic properties of drugs, and minimize off-target side effects. Nanotechnology provides efficacy and safety of nano-enabled therapies for treating brain tumors.
Topics & Concepts
Blood–brain barrierNanotechnologyMedicineBrain tumorNeuroscienceMaterials scienceCentral nervous systemBiologyPathologyInternal medicineNanoparticle-Based Drug DeliveryAdvanced biosensing and bioanalysis techniquesNanoplatforms for cancer theranostics