Targeting telomerase reverse transcriptase with the covalent inhibitor NU-1 confers immunogenic radiation sensitization
Yue Liu, Rick C. Betori, Joanna Pagacz, Grant B. Frost, Elena V. Efimova, Ding Wu, Donald J. Wolfgeher, Tracy M. Bryan, Scott B. Cohen, Karl A. Scheidt, Stephen J. Kron
Topics & Concepts
TelomereTelomeraseTelomerase reverse transcriptaseImmune systemCancer researchDNA damageCancerReverse transcriptaseSensitizationSenescenceBiologyImmunologyMolecular biologyDNACell biologyGeneticsPolymerase chain reactionGeneTelomeres, Telomerase, and SenescenceCancer Research and TreatmentsImmunotherapy and Immune Responses