Are micronutrient levels and supplements causally associated with the risk of Alzheimer's disease? A two-sample Mendelian randomization analysis
Lei Meng, Zhe Wang, Yu-Cheng Ming, Liang Shen, Hong‐Fang Ji
Abstract
-value = 0.046). In conclusion, the present analysis indicated that among the vitamins and minerals, vitamin D and copper levels exhibited negative causal associations with AD risk, which may help in better use of micronutrients to prevent AD and require further verification by further studies.
Topics & Concepts
Mendelian randomizationMicronutrientDiseaseAlzheimer's diseaseMedicineSample (material)RandomizationBiologyGeneticsRandomized controlled trialInternal medicinePathologyGenotypeGeneGenetic variantsChemistryChromatographyFolate and B Vitamins ResearchNutritional Studies and DietNutrition, Genetics, and Disease