Single-cell nascent transcription reveals sparse genome usage and plasticity
Shaoqian Ma, Yantao Hong, Junhan Chen, Jingzhao Xu, Xiaohua Shen
Topics & Concepts
BiologyIntergenic regionTranscription (linguistics)GeneticsGenomeGeneRNANon-coding RNAComputational biologyInduced pluripotent stem cellTranscription factorLong non-coding RNATranscriptional regulationRegulation of gene expressionTranscriptomeHuman genomeGeneral transcription factorGenomicsRegulatory sequenceGene expressionDeep sequencingEpigeneticsCell biologyAdvanced biosensing and bioanalysis techniquesSingle-cell and spatial transcriptomics