Modulating biological aging with food-derived signals: a systems and precision nutrition perspective
Carsten Carlberg, Andreas Blüthner, Irini Schoeman-Giziakis, Annemarie Oosting, Luca Cocolin
Abstract
Lifespan extension has not prevented age-related decline. We propose that diet acts as a molecular modulator of aging, influencing inflammation, the microbiome, and systemic resilience. Biological age markers and AI-powered multi-omics reveal actionable dietary targets, including food-derived signals and Nutrition Dark Matter. We highlight precision nutrition and the EIT Food Healthy Aging Think & Do Tank as pathways to align science, policy, and practice for healthy aging.
Topics & Concepts
Resilience (materials science)Perspective (graphical)MicrobiomeHealthy agingPsychological resilienceBiologyPsychologyNeuroscienceComputational biologyMedicineGerontologyBioinformaticsComputer scienceArtificial intelligenceSocial psychologyMaterials scienceComposite materialNutrition, Genetics, and DiseaseGenetics, Aging, and Longevity in Model OrganismsNutritional Studies and Diet