Structure of adenylyl cyclase 5 in complex with Gβγ offers insights into ADCY5-related dyskinesia
Yu‐Chen Yen, Yong Li, Chun-Liang Chen, Thomas Klose, Val J. Watts, Carmen Dessauer, J.J.G. Tesmer
Topics & Concepts
Adenylyl cyclaseHeterotrimeric G proteinGene isoformAllosteric regulationGs alpha subunitCell biologyG protein-coupled receptorBiologyCoiled coilG proteinChemistryBiophysicsBiochemistrySignal transductionReceptorGeneProtein Kinase Regulation and GTPase SignalingIon channel regulation and functionReceptor Mechanisms and Signaling