Transaminitis is an indicator of mortality in patients with COVID-19: A retrospective cohort study
Vishnu Charan Suresh Kumar, Prateek S. Harne, Samiran Mukherjee, Kashvi Gupta, Umair Masood, Anuj Vikrant Sharma, Jivan Lamichhane, Amit S. Dhamoon, Bishnu Sapkota
Abstract
BACKGROUND: Since its discovery in Wuhan, China in December of 2019, the novel coronavirus has progressed to become one of the worst pandemics seen in the last 100 years. Recently, there has been an increased interest in the hepatic manifestations of coronavirus disease 19 (COVID-19). AIM: To describe the demographic and clinical characteristics of COVID-19 positive patients and study the association between transaminitis and all-cause mortality. METHODS: -test were used for comparing non-parametric and parametric continuous variables respectively and a multivariable logistic regression models to study the association between transaminitis and mortality using SAS version 9.4 (SAS Institute, Cary, NC, United States). RESULTS: = 0.03). CONCLUSION: Our study showed that transaminitis on admission was associated with severe clinical outcomes such as admission to the intensive care unit, need for mechanical ventilation, and mortality.