The <i>FAM171A2</i> gene is a key regulator of progranulin expression and modifies the risk of multiple neurodegenerative diseases
Wei Xu, Sida Han, Can Zhang, Jieqiong Li, Yan‐Jiang Wang, Chen‐Chen Tan, Hong-Qi Li, Qiang Dong, Cui Mei, Lan Tan, Jin‐Tai Yu
Abstract
The FAM171A2 gene is a key regulator of progranulin expression and modifies the risk of multiple neurodegenerative diseases.
Topics & Concepts
BiologyFrontotemporal dementiaRegulatorDiseaseGeneGenome-wide association studyPhenotypeDementiaMicrogliaMutationGeneticsImmunologyMedicineInflammationSingle-nucleotide polymorphismInternal medicineGenotypeAmyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatmentsParkinson's Disease Mechanisms and Treatments