Evaluation of substituent bioactivity and anion impact of linear and T-shaped silver(<scp>i</scp>) pyridinyl complexes as potential antiproliferative, antioxidant, antimicrobial agents and DNA- and BSA-binders
Adesola A. Adeleke, Md. Shahidul Islam, Kolawole A. Olofinsan, Veronica F. Salau, Chunderika Mocktar, Bernard Omondi
Abstract
The impact of ligand substituents and anion variation on the bio-activity of pyridinyl Ag(I) complexes was evaluated. The complexes showed potential therapeutic ability with notable anticancer, antioxidant, and antimicrobial activities.
Topics & Concepts
ChemistryAntimicrobialSubstituentAntioxidantLigand (biochemistry)Combinatorial chemistryDNAIonStereochemistryMedicinal chemistryBiochemistryOrganic chemistryReceptorMetal complexes synthesis and propertiesSynthesis and Characterization of Heterocyclic CompoundsComputational Drug Discovery Methods