Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics
Laura N. Scott, Monice Fiume, Wilma F. Bergfeld, D. Belsito, Ronald A. Hill, Curtis D. Klaassen, D.C. Liebler, James G. Marks, Ronald C. Shank, Thomas J. Slaga, Paul W. Snyder, Bart Heldreth
Abstract
The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of Panthenol, Pantothenic Acid, and 5 derivatives as used in cosmetics. These ingredients named in this report are reported to function in cosmetics as hair conditioning agents, and Panthenol also is reported to function as a skin-conditioning agent-humectant and a solvent. The Panel reviewed relevant data for these ingredients, and concluded that these 7 ingredients are safe in cosmetics in the present practices of use concentration described in this safety assessment.
Topics & Concepts
CosmeticsPantothenic acidChemistryPharmacologyToxicologyMedicineFood scienceOrganic chemistryBiologyRiboflavinEffects and risks of endocrine disrupting chemicalsPharmaceutical studies and practicesAnimal testing and alternatives