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Engineered LwaCas13a with enhanced collateral activity for nucleic acid detection

Jie Yang, Yang Song, Xiangyu Deng, Jeffrey A. Vanegas, Zheng You, Yuxuan Zhang, Zhengyan Weng, Lori Avery, Kevin D. Dieckhaus, Advaith Peddi, Yang Gao, Yi Zhang, Xue Gao

2022Nature Chemical Biology107 citationsDOIOpen Access PDF

Topics & Concepts

Nucleic acidCollateralCollateral damageComputational biologyNucleic acid detectionChemistryBiochemistryBiologyBusinessSociologyFinanceCriminologyAdvanced biosensing and bioanalysis techniquesCRISPR and Genetic EngineeringRNA and protein synthesis mechanisms
Engineered LwaCas13a with enhanced collateral activity for nucleic acid detection | Litcius