An outbreak of a novel recombinant Coxsackievirus A4 in a kindergarten, Shandong province, China, 2021
Juan Li, NI Nan, Yanan Cui, Shuai Zong, Xue Yao, Tao Hu, Mengyuan Cao, Yong Zhang, Peiqiang Hou, Michael J. Carr, Weijia Xing, Hong Zhou, Weifeng Shi
Abstract
In 2021, twenty children exhibiting influenza-like illnesses were reported from a kindergarten in Shandong Province, China. Eleven genomes of Coxsackievirus A4 (CV-A4) were obtained from the pediatric cases, sharing <93% genome sequence identities with known CV-A4 strains. Further analyses suggested potential genetic recombination in the P3 region of the novel strains.
Topics & Concepts
OutbreakCoxsackievirusVirologyChinaGenomeBiologyRecombinant DNAGeneticsEnterovirusGeneVirusGeographyArchaeologyViral Infections and Immunology ResearchRespiratory viral infections researchViral gastroenteritis research and epidemiology