Palladium-catalyzed [2 + 2 + 1] annulation: access to chromone fused cyclopentanones with cyclopropenone as the CO source
Wen-Qing Zhu, Yu-Chen Fang, Wen‐Yong Han, Fei Li, Min‐Ge Yang, Yong‐Zheng Chen
Abstract
A variety of chromone fused cyclopentanones are efficiently generated in good to high yields <italic>via</italic> palladium-catalyzed [2 + 2 + 1] annulation, in which cyclopropenone was utilized for the first time as the sole CO surrogate in the carbonylation process.
Topics & Concepts
ChromoneChemistryAnnulationPalladiumCarbonylationCatalysisOrganic chemistryMedicinal chemistryCombinatorial chemistryCarbon monoxideCatalytic C–H Functionalization MethodsCatalytic Alkyne ReactionsCatalytic Cross-Coupling Reactions