Increased circulating T follicular helper 13 subset correlates with high IgE levels in pediatric allergic asthma
Xiao Tong, Chaojiao Guan, Tuo Ji, Cheng Cao, Junfeng Jiang, Min Liu, Qin Guo, Pengcheng Zhou, Fang Gong
Abstract
We found an elevation of circulating TFH13 cell subset in asthmatic children and the frequency of TFH13 cells positively correlated with the plasma dust mite-specific IgE levels. These results indicated that TFH13 cell subset may be responsible for the immunopathogenesis of excessive IgE accumulation in children with allergic asthma. The authors declare no conflict of interest. The peer review history for this article is available at https://publons.com/publon/10.1002/eji.202250076 Data from this study are available upon reasonable request. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.