Is there a causal relationship between hypothyroidism and hyponatremia?
Julie Chen
Abstract
Hyponatremia is one of the most common lab abnormalities seen in clinical practice. It has become widely accepted that hypothyroidism is a cause of euvolemic hyponatremia. The primary mechanism is thought to be due to impaired free water excretion and changes in sodium handling in the kidney. However, the clinical studies are conflicting and do not definitively confirm the association between hypothyroidism and hyponatremia. Therefore, if severe hyponatremia occurs in a patient without myxedema coma, other potential etiologies should be sought.
Topics & Concepts
HyponatremiaMedicineEtiologyMyxedemaIntensive care medicineComa (optics)Clinical PracticeInternal medicinePediatricsThyroidFamily medicineOpticsPhysicsElectrolyte and hormonal disordersRenal function and acid-base balanceBiomedical and Chemical Research