Effect of Human Plasma on Hepatic Uptake of Organic Anion–Transporting Polypeptide 1B Substrates: Studies Using Transfected Cells and Primary Human Hepatocytes
Yi‐An Bi, Sangwoo Ryu, David A. Tess, A. David Rodrigues, Manthena V. S. Varma
Topics & Concepts
HEK 293 cellsHepatocyteChemistryTransfectionIn vivoOrganic anion-transporting polypeptideIn vitroPharmacokineticsCell cultureBiophysicsMolecular biologyPharmacologyBiochemistryBiologyReceptorTransporterGeneGeneticsBiotechnologyDrug Transport and Resistance MechanismsRenal Transplantation Outcomes and TreatmentsPharmacogenetics and Drug Metabolism