Cytotoxic mechanisms of doxorubicin at clinically relevant concentrations in breast cancer cells
Rachel E. Nicoletto, Clyde M. Ofner
Topics & Concepts
DoxorubicinCytotoxic T cellCytotoxicityTopoisomeraseBreast cancerMechanism of actionCancer researchOxidative stressPharmacologyCancerCancer cellChemistryDNA damageApoptosisMedicineChemotherapyInternal medicineBiochemistryDNAIn vitroChemotherapy-induced cardiotoxicity and mitigationCancer Treatment and PharmacologyCancer therapeutics and mechanisms