Mechanochemical and aging-based reductive amination with chitosan and aldehydes affords high degree of substitution functional biopolymers
Galen Yang, Sophie Régnier, Noah Huin, Tracy Liu, Edmond Lam, Audrey Moores
Abstract
A solid-phase method favors the formation of Shiff-bases from chitosan and aldehydes and subsequent reduction. This provides access to alkylated chitosans with high degrees of functionalization with low process mass intensity.
Topics & Concepts
Reductive aminationAminationSubstitution (logic)ChitosanChemistryDegree (music)Organic chemistryCombinatorial chemistryCatalysisComputer sciencePhysicsAcousticsProgramming languageChemical Synthesis and ReactionsCarbon dioxide utilization in catalysisbiodegradable polymer synthesis and properties