Two-Photon Light-Activatable Fluorophores for Organelle Imaging in Living Cells and Tissue-Level Imaging
Zhuang Ma, Zhangcheng Fu, Boxuan Hou, Xueying Zeng, Junqiao Wang, Ying Tan, Yuyang Jiang, Naihan Xu, Chunyan Tan
Abstract
, they supported high-resolution, three-dimensional structural imaging of subcutaneous tumors with minimal background. The findings highlight the potential of these PAFs for high-resolution, organelle, and deep-tissue imaging, offering a versatile platform for studying subcellular dynamics with applications in biomedical research.
Topics & Concepts
ChemistryOrganelleEndoplasmic reticulumBiophysicsLysosomeNanotechnologyMolecular imagingMembraneSubcellular localizationCytoplasmCell biologyMoleculeLive cell imagingCell membraneCellular compartmentMicroscopyMembrane contact sitePhotochromic and Fluorescence ChemistryPhotoreceptor and optogenetics researchLuminescence and Fluorescent Materials